Opportunity

Simpler Grants.gov #RFA-AI-28-005

NIH research funding to continue the Immune Tolerance Network and develop immune-tolerance therapies

Buyer

National Institutes of Health

Posted

October 20, 2026

Respond By

January 29, 2027

Identifier

RFA-AI-28-005

NAICS

541715

The National Institutes of Health is seeking applications to continue the Immune Tolerance Network and advance therapies for immune-mediated disorders. - Government buyer: National Institutes of Health (NIH), through its Division of Allergy, Immunology and Transplantation (DAIT). - Opportunity type: Research funding through a cooperative agreement, not a product procurement. - Program: Continue the Immune Tolerance Network (ITN), developing tolerogenic therapies for allergic diseases and asthma, autoimmune diseases, and immune-mediated consequences of transplantation. - Core work: Design and conduct clinical trials, share trial results, and perform integrated mechanistic studies. - Funding and award: $21,986,000 in program funding; one award is anticipated. - OEMs and vendors: No manufacturers, vendors, or resellers are identified. - Products and quantities: No products, part numbers, or product quantities are specified.

Description

This notice supports applications to continue the Immune Tolerance Network (ITN), whose primary objective is to develop tolerogenic therapies for immune-mediated disorders. The work covers allergic diseases and asthma, autoimmune diseases, and immune-mediated consequences of transplantation. ITN core functions include designing, conducting, and sharing clinical trial results and performing integrated mechanistic studies. Program funding is $21,986,000, with one expected award.

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