SAM #D-26-DO-0018

DEA requests custom synthesis of pharmacological substances for testing

The U.S. Drug Enforcement Administration (DEA), under the Department of Justice, is seeking laboratory synthesis services for a range of pharmacological substances to support its Chemical Control Unit. - Government Buyer: - U.S. Drug Enforcement Administration (DEA), Office of Acquisition and Relocation Management - Contact: Ms. Angel Barkley - OEMs and Vendors: - No specific OEMs or commercial manufacturers are named; the requirement is for specialized laboratory synthesis, typically fulfilled by chemical synthesis labs or specialty pharmaceutical manufacturers. - Products/Services Requested: - Synthesis of 15 distinct pharmacological substances, each in small quantities (mostly 1g or 200mg) - Substances include N-sec-butyl Butylone (hydrochloride), Methiodone (hydrochloride), 5-chloro Desmethyl Chlorphine, Spirofluorphine, Despropionyl Bezitramide, Methoxyorphine, Methylorphine, nor-Spiroorphine, N-Propionitrile Brorphine (hydrochloride), N-Propionitrile Methylorphine (hydrochloride), 5,6-dichloro Desmethylbrorphine, Cyclopropylflualprazolam, 4-bromo-Deschloroalprazolam, Mexazolam, and an unspecified substance - Each item is identified by a unique part number - Unique/Notable Requirements: - All substances are to be synthesized for pharmacological testing purposes - Award will be made on a lowest price technically acceptable basis, considering technical acceptability, past performance, and price - NAICS code 325199 (Other Basic Organic Chemical Manufacturing) applies - Delivery required by January 31, 2027 - The procurement is unrestricted, open to qualified laboratory synthesis providers - Technical Information: - Quantities are small, indicating research or testing use - Some substances are rare or custom-synthesized, requiring specialized expertise - No commercial off-the-shelf products; all items are custom laboratory syntheses

Description

Synthesis of Substances for Pharmacological Testing

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