# SAM #D-26-DO-0018

DEA Solicitation for Synthesis of Pharmacological Substances

**Buyer:** DEA Headquarters
**Posted:** September 23, 2026
**Respond By:** September 25, 2026
**Identifier:** D-26-DO-0018
**NAICS:** 325199

The U.S. Drug Enforcement Administration (DEA), under the Department of Justice, is soliciting synthesis services for a range of specialized pharmacological substances to support the DEA Chemical Control Unit's research and testing activities.
- Government Buyer:
  - U.S. Drug Enforcement Administration (DEA), Office of Acquisition and Relocation Management
  - Department of Justice
- Products/Services Requested:
  - Synthesis of 15 distinct chemical substances, each in a quantity of 1 unit (typically 1g or 200mg)
    - Examples include N-sec-butyl Butylone (hydrochloride), Methiodone (hydrochloride), 5-chloro Desmethyl Chlorphine, Spirofluorphine, Despropionyl Bezitramide, Methoxyorphine, Methylorphine, nor-Spiroorphine, N-Propionitrile Brorphine (hydrochloride), and others
    - Each item is identified by a unique part number
- Unique/Notable Requirements:
  - All substances are to be synthesized specifically for pharmacological testing
  - Award will be made on a lowest price technically acceptable basis, considering technical acceptability, past performance, and price
  - The procurement is unrestricted and uses NAICS code 325199 (All Other Basic Organic Chemical Manufacturing)
  - Delivery of all substances is required by the specified deadline
- OEMs/Vendors:
  - No specific OEMs or vendors are named; the requirement is for custom synthesis, so qualified chemical manufacturers or laboratories are eligible
- The opportunity is open to all qualified sources capable of synthesizing the listed substances to required specifications

### Description

<p>Synthesis of Substances for Pharmacological Testing</p>

[View original listing](https://sam.gov/opp/3862cbaab0b443d58864e8d43476b673/view)