Federal Register #2026-21905

NIH Licensing and Research Collaboration Opportunity for Wb4B Filariasis Detection Technology

The National Institutes of Health is offering a lymphatic filariasis detection technology for licensing and research collaboration. - Government organizations: U.S. Department of Health and Human Services (HHS), through the National Institutes of Health (NIH) and National Institute of Allergy and Infectious Diseases (NIAID). - Technology offered: Government-owned “Compositions and Methods for Detecting Lymphatic Filariasis,” based on the Wb4B antigen and related expression plasmids, for detecting infection caused by Wuchereria bancrofti or Brugia malayi. - Potential uses include diagnosis and disease surveillance; the pre-clinical technology aims to address cross-reactivity limitations in existing diagnostics. - The notice identifies HHS Reference No. E-067-2024-0 and patent filings U.S. Provisional Patent Application No. 63/672,667 and PCT Application No. PCT/US2025/037585. - Potential combinations with related NIAID technologies Wb123 and Wb5 are noted. - Opportunity sought: Interested parties may license, further develop, evaluate, or commercialize the technology through collaboration. - OEMs and vendors: No commercial OEMs, vendors, or resellers are named. - Quantities and part numbers: No purchase quantities or commercial product part numbers are specified.

Description

The National Institutes of Health notice announces that a government-owned invention is available for licensing and collaborative research. The technology, “Compositions and Methods for Detecting Lymphatic Filariasis,” is intended to detect infection with Wuchereria bancrofti or Brugia malayi and addresses cross-reactivity limitations in existing diagnostics. The notice describes potential diagnostic and surveillance applications, a pre-clinical development stage, and licensing and research collaboration contacts. The technology is identified as HHS Reference No. E-067-2024-0.

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