Opportunity
Simpler Grants.gov #RFA-NS-28-010
NIH BRAIN Initiative funding for invasive human brain recording and stimulation research
Buyer
National Institutes of Health
Posted
September 30, 2026
Respond By
February 08, 2029
Identifier
RFA-NS-28-010
NAICS
541715
The NIH BRAIN Initiative is seeking research applications on mechanisms of human brain function using invasive opportunities in clinical settings. - Government buyer: National Institutes of Health (NIH), through the Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) Initiative; solicitation RFA-NS-28-010. - Opportunity type: Research funding, not a purchase of products or services. - Research sought: Mechanistic studies of human brain function using approaches such as intracranial recording or stimulation during invasive procedures. Projects may also combine complementary experimental models or systems and should be rigorous, innovative, and informed by theoretical constructs or quantitative mechanistic models. - Program scale: $8 million in listed program funding, with five awards anticipated. This is program funding, not an estimated procurement contract value. - Awardee requirements: Funded investigators will participate in an NIH-coordinated consortium working group addressing practice standards, neuroethical considerations, ancillary data collection, and data standardization and dissemination. - OEMs and vendors: No manufacturers, commercial vendors, products, or product quantities are identified.
Description
This funding opportunity supports transformative, mechanistic research into human brain function, including how neural activity relates to internal experiences and observable behaviors. Studies are expected to leverage invasive procedures in humans, such as intracranial recording or stimulation, and may incorporate complementary experimental models or systems. Proposed approaches should be rigorous, innovative, and guided by theoretical constructs or quantitative mechanistic models. Funded investigators will participate in an NIH-coordinated consortium working group addressing practice standards, neuroethics, ancillary data collection, and data standardization and dissemination.