SAM #75N98026Q01251

Laboratory Testing Services for DMPK Assays and Pharmacokinetic Studies

The National Institutes of Health (NIH) Office of the Director, Office of Acquisitions, is seeking a firm-fixed-price contract for specialized laboratory testing services to support medicinal chemistry projects targeting metabolic and alcohol use disorders. - Government Buyer: - National Institutes of Health (NIH) - Office of the Director - Office of Acquisitions - Services Requested: - Orthogonal Assay Development & Laboratory Testing Services - Grouped DMPK (Drug Metabolism and Pharmacokinetics) assays - Caco-2 Permeability Assay - Plasma protein binding assay - Hepatic metabolic stability assay - Pharmacokinetic study in C57BL6 mice - Purpose: Assess drug absorption and stability for novel therapeutic compounds - Contract Details: - Firm-fixed-price contract - One-year period of performance - Estimated contract value up to $350,000 - Unique Requirements: - Assays must support evaluation of compounds for metabolic and alcohol use disorder research - Laboratory must be capable of performing grouped DMPK assays and in vivo pharmacokinetic studies - OEMs and Vendors: - No specific OEMs or vendors are named; open to qualified laboratory service providers

Description

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