Miami University and Ohio University Ionwave #0920262475

Miami University seeks high-sensitivity, inverted laser-scanning confocal microscope for advanced research imaging

Miami University, through its Center for Advanced Microscopy and Imaging (CAMI), is seeking proposals for a high-sensitivity, inverted laser-scanning confocal microscope to enhance its research core capabilities. - Government Buyer: - Miami University, Center for Advanced Microscopy and Imaging (CAMI), Office of Strategic Procurement - Products Requested: - Fully integrated inverted laser-scanning confocal microscope with super-resolution capability - Seven fluorescence detectors (including broadband spectral and far-red/NIR optimized detectors) - High-sensitivity silicon-photomultiplier technology and photon-counting detection - Integrated excitation lasers (405, 445, 488, 514, 561, 640, 785 nm) - Objectives for various magnifications and immersion types - Hardware-based infrared Z-drift compensation and environmental controls for live imaging - Closed-loop piezo Z-axis nanopositioning - High-brightness LED transmitted illumination and widefield fluorescence - Comprehensive software for acquisition, analysis, and automated imaging - Dedicated acquisition workstation with high-performance specifications - Services Requested: - Delivery, installation, optical alignment, and commissioning - On-site and continued applications training for multi-user operation - Regional technical/applications support, troubleshooting, and preventive maintenance options - Unique Requirements: - System must support advanced fluorescence imaging (spectral, super-resolution, NIR, FRET, live-cell, thick-tissue, automated multidimensional acquisition) - Emphasis on reproducible detector performance, ultra-low noise, broad dynamic range, and ease of use for multi-user environments - Robust training and long-term technical support - No specific OEMs or part numbers are mentioned; opportunity is open to qualified manufacturers capable of meeting detailed technical specifications.

Description

Miami University is seeking proposals for a high-sensitivity, inverted laser-scanning confocal microscope for use in the Center for Advanced Microscopy and Imaging (CAMI). The system will serve as a multi-user research core instrument and must support quantitative spectral fluorescence imaging, high-speed resonant and galvanometer scanning, super-resolution imaging, near-infrared detection, FRET, live-cell and live-organism imaging, thick-tissue and whole-mount imaging, automated multidimensional acquisition, and offline quantitative image analysis. The procurement aims to improve detection of weak signals, enable quantitative and reproducible fluorescence measurements, expand high-speed and live-imaging capacity, and support advanced applications including spectral unmixing, FRET, NIR imaging, and super-resolution microscopy. Award will be based on best value selection considering price, delivery, quality, ease of use, installation cost, and reliability.

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