SAM #75N98026Q01153

Chromatin immunoprecipitation sequencing laboratory services for mouse stem cell genetic material binding analysis

This opportunity from the National Institutes of Health (NIH), Office of Logistics and Operations (OLAO), Hospital and Laboratory Support Division, seeks specialized laboratory services for chromatin immunoprecipitation sequencing to support mouse stem cell research. - Government Buyer: - National Institutes of Health (NIH) - Office of Logistics and Operations (OLAO) - Hospital and Laboratory Support Division - OEMs and Vendors: - Active Motif (laboratory services provider) - Products/Services Requested: - Chromatin immunoprecipitation sequencing laboratory services - Includes antibody qualification and sequencing to characterize EXOSC10 protein binding patterns - Supports analysis of genetic material binding in mouse embryonic stem cells - No specific part numbers or product SKUs provided - Quantity not specified - Unique/Notable Requirements: - Services are for research on the EXOSC10 protein's role in genome stability and DNA repair - Utilizes custom mouse embryonic stem cell lines with a three-times FLAG tag for EXOSC10 - Matched control cell lines expressing green fluorescent protein with the same tag will be used - Procurement is non-competitive and classified under NAICS code 811210 - No physical products requested, only specialized laboratory sequencing services

Description

General Information

Document Type:

Presolicitation

Synopsis Number:

75N98026Q01153

Posted Date:

September 8, 2026

Original Response Date:

September 18, 2026

Current Response Date:

September 18, 2026

Set Aside:

N/A

NAICS Code:

811210

Contracting Office Address

National Institutes of Health (NIH), Office of the Director (OD)

Office of Logistics and Operations (OLAO)

Office of Acquisition and Logistics Management (OALM)

Hospital and Laboratory Support Division

6701 Rockledge Drive

Bethesda, MD 20817 

Description

INTRODUCTION

THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS TO AWARD A CONTRACT OR PURCHASE ORDER WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME).

The National Institutes of Health (NIH) intends to negotiate and award a contract without providing for full and open competition (Including brand-name) to:

Active Motif

1914 Palomar Oaks Way

Suite 150

Carlsbad, California 92008

NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE

The intended procurement is classified under NAICS code 811210 with a Size Standard $1000.

REGULATORY AUTHORITY

The resultant contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 2026-01, March 13, 2026. This acquisition is conducted under the procedures as prescribed in FAR subpart 13-Simplified Acquisition Procedures at an amount not exceeding the simplified acquisition threshold ($350,000).

STATUTORY AUTHORITY

This acquisition is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures, Subpart 13.106-1 (b) (1), Soliciting from a single source and is not expected to exceed the simplified acquisition threshold. Contracts awarded using FAR Part 13-Simplified Acquisition Procedures are exempt from the requirements of FAR Part 6-Competition Requirements.

GENERAL INFORMATION

Title: Chromatin immunoprecipitation sequencing laboratory services for genetic material binding analysis in mouse stem cells Background Information: The National Institute of Diabetes and Digestive and Kidney Diseases is conducting research to better understand how the EXOSC10 protein contributes to genome stability during the repair of deoxyribonucleic acid damage. To support this research, the laboratory developed a mouse embryonic stem cell line in which the EXOSC10 protein contains a three-times FLAG tag, allowing the protein to be detected and enriched using an anti-FLAG antibody. Because the genome-wide binding pattern of EXOSC10 has not been fully characterized, antibody qualification is required before conducting chromatin immunoprecipitation sequencing. Matched control cell lines expressing green fluorescent protein with the same three-times FLAG tag will be used to distinguish specific EXOSC10 binding from background signal and ensure reliable experimental results..

CLOSING STATEMENT

This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement and include a technical proposal, a cost-price proposal, the period of performance, the Unique Entity ID (UEI), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.

A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement.

All responses must be received by September 18, 2026 at 9:00 AM Eastern time and must reference solicitation number 75N98026Q01153. Responses may be submitted electronically to Mr. James Law, Contracting Officer at James.Law@nih.gov. Fax responses will not be accepted.

"All responsible sources may submit a capability statement, proposal, or quotation, which shall be considered by the agency.

View original listing