Opportunity

Simpler Grants.gov #PAR-27-065

NIH NINDS Solicitation for Investigator-Initiated Clinical Trials

Buyer

National Institutes of Health

Posted

August 31, 2026

Respond By

March 09, 2029

Identifier

PAR-27-065

NAICS

541715

NIH's National Institute of Neurological Disorders and Stroke (NINDS) is inviting applications for investigator-initiated clinical trials focused on neurological diseases. - Government buyer: - National Institutes of Health (NIH) - National Institute of Neurological Disorders and Stroke (NINDS) - Scope of opportunity: - Clinical trials involving small molecules, biologics, medical devices, and therapies (surgical, behavioral, diet-based, rehabilitation) - Both exploratory (early/middle phase) and confirmatory (Phase 3/comparative effectiveness) trials - Products/services requested: - No specific products, part numbers, or quantities listed - Service: Clinical trial execution for neurological disorder interventions - OEMs and vendors: - No OEMs or vendors specified - Unique requirements: - Broad eligibility: government, business, nonprofit, educational organizations - Special rules for foreign organizations and international collaborations - Studies must align with NINDS mission and research interests - No administrative or procedural details included in requirements

Description

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated clinical trials to the National Institute of Neurological Disorders and Stroke (NINDS). The trials must address questions within the mission and research interests of NINDS and may include studies of small molecules, biologics, devices, surgical, behavioral, diet-based, or rehabilitation therapies. Studies addressing neurological diseases and care across the lifespan are highly encouraged. The notice invites early- and middle-phase exploratory clinical trials as well as later phase confirmatory Phase 3 or comparative effectiveness clinical trials.

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