Opportunity
Simpler Grants.gov #PAR-27-053
NIH Grant Opportunity for Exploratory Clinical Neuroscience Research on Substance Use Disorders (R61/R33 Clinical Trial Optional)
Buyer
National Institutes of Health
Posted
August 31, 2026
Respond By
June 16, 2028
Identifier
PAR-27-053
NAICS
541715
This opportunity from the National Institutes of Health (NIH) seeks applications for exploratory and developmental clinical research on substance use disorders (SUD). - Government Buyer: - National Institutes of Health (NIH), Division of Neuroscience and Behavior - Products/Services Requested: - Clinical research projects investigating neurobiological mechanisms, circuitry, and behavior related to SUD - Supported under the R61/R33 Phased Innovation Award activity code - OEMs and Vendors: - No specific OEMs or vendors are mentioned, as this is a grant for research activities - Unique/Notable Requirements: - Open to a wide range of organizations, including domestic and foreign entities - NIH will not issue awards involving foreign subawards/subcontracts unless submitted under a designated NOFO for international collaborations - Applicants not requiring a phased research approach should apply under a different activity code - Focus is on fundamental research, not procurement of products or equipment
Description
This notice of funding opportunity (NOFO) supports exploratory and developmental clinical research applications focusing on understanding the neurobiological mechanisms underlying substance use disorders (SUD), including fundamental circuitry and behavior relevant to substance use. It uses a R61/R33 Phased Innovation Award activity code. Applicants not requiring a phased research approach are encouraged to apply under a different funding activity code. The funding is provided as a grant with no cost sharing or matching requirement.