SAM #NCI09567

Procurement of Laboratory Microtome for NCI Bladder Cancer Research

This procurement opportunity is issued by the National Cancer Institute (NCI), specifically the Bladder Cancer Section within the Center for Cancer Research, to acquire a laboratory microtome for advanced tissue analysis. - Government Buyer: - National Cancer Institute (NCI), Center for Cancer Research, Bladder Cancer Section - Office of Logistics and Acquisition Operations (OLAO) - Products Requested: - Laboratory microtome (1 unit) - For precise, reproducible sectioning of paraffin-embedded tissue specimens - Supports histologic evaluation and immunohistochemistry - Must offer: - Precise section thickness control - Stable specimen orientation - Secure blade holder with safety features - Ergonomic design for repeated laboratory use - Reliable mechanical performance - New equipment only, with warranty and documentation - Services Requested: - Delivery, installation, operational verification, and debris removal within 1 business day of scheduled delivery - Unique Requirements: - Equipment must be new and fully functional - Vendor must provide all supporting documentation and warranty information - Delivery, setup, and acceptance required within 30-45 days from order placement - Debris removal and operational verification included - No specific OEMs, brands, or part numbers are mentioned - Only one microtome is requested; no additional accessories or consumables specified

Description

The purpose of this project is to acquire one laboratory microtome for preparation of thin, reproducible tissue sections from paraffin-embedded specimens used in the Bladder Cancer Section's research. The microtome will support histologic evaluation, immunohistochemistry, and other tissue-based analyses needed to study mechanisms of resistance to antibody-drug conjugates (ADCs) in bladder tumors. A dedicated microtome is justified to enable timely, consistent in-house sectioning of valuable research specimens, reduce dependence on shared equipment or external sectioning, and improve experimental reproducibility and workflow efficiency.

The microtome must provide precise and reproducible section thickness control suitable for routine histology and research applications using paraffin-embedded tissue. The unit should provide stable specimen orientation and controlled sectioning, a secure blade holder with appropriate safety features, and an ergonomic design suitable for repeated laboratory use. Reliable mechanical performance is essential to produce intact, uniform tissue sections for downstream staining, imaging, and quantitative analysis.  

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