SAM #75N98026Q01018CELLINKNCI09639

Procurement of Cellink BIO X Advanced Multi-Material 3D Bioprinting System for NIH Cancer Research

The National Institutes of Health (NIH), Office of the Director, Office of Logistics and Operations (OLAO), is seeking to procure a high-precision 3D bioprinting system for advanced cancer biology and organoid research. - Government Buyer: - National Institutes of Health (NIH) - Office of the Director (OD) - Office of Logistics and Operations (OLAO), Office of Acquisition and Logistics Management (OALM), Hospital and Laboratory Support Division - OEM Highlighted: - Cellink LLC (manufacturer of the requested system) - Products Requested: - Cellink BIO X Advanced Multi-Material 3D Bioprinting System - Quantity: 1 unit - Description: High-precision 3D bioprinting platform for reproducible fabrication of multicellular tissue constructs using various bioinks and biomaterials; compatible with cell culture, microscopy, and molecular analysis workflows - Notable Requirements: - System must support standardized, reproducible production of physiologically relevant in vitro models - Integration with existing laboratory workflows is essential - Intended for NIH-funded cancer biology and organoid research - No specific part numbers provided - Procurement is expected to not exceed the simplified acquisition threshold

Description

THE LABORATORY INVESTIGATES MECHANISMS FO TUMORS INITIATIONS PROGRESSION AND THERAPEUTIC RESPONSE USING ADVANCED THREE DIMENSIONAL(3d) CULTURE SYSTEMS ORGANID MODELS AND ENGINEERED TISSUE MICRONMENTS . CURRENT RESEARCH FOCUESES ON UNDERSTANDING INTERACTIONS BETWEEN TUMORS CELLS AND THERI SURROUNDING STROMAL AND EXTRACULLULAR MATRIX ENVIRONMENTS THAT INFLUENCE CANCER DEVELOPMENT AND TREATMENT RESPONSE. EXISTING LABORATORY METHODS FOR GENERATING 3D TISSUEMODELS RELYON MANUAL PREPRATION TECHNIQUES THAT INTRODUCE VARIABILITY IN CONSTRUCT GEOMETRY, CELL DISTRUBUTION, AND EXTRACELLULAR MATRIX COMPOSITION.  THESE LIMITATIONS REDUCE EXPERIMENTAL REPRODUCIBILITY AND RESTRICT THE COMPLEXITY OF TISSUE MODELS THAT CAN BE GENERATED.  TO SUPPORT ONGOING  NIH-FUNDED RESEARCH, THEMUTHUSWAMY LABORATORY REQUIRES A HIGH-PRECISION 3DE BIOPRINTING PLATFORM CAPABLE OF REPRODUCIBLY FABRICATING MULTICELLULAR TISSUE CONSTRUCTS USING A VARIETY OF BIOMARKS AND BIOMATERIALS.  THE SYSTEM MUST INTEGRATE WITH EXISTING CELL CULTURE, MICROSCOPY, AND DOWNSTREAM MOLECULAR ANALYSIS WORKFLOWS WHILE ENABLING STANDARDIZED PRODUCTION OF PHYSIOLOGICALLY RELEVENT INVITRO MODELS.

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