SAM #1333ND26QNB640412

NIST Solicitation for Oxford Instruments Andor CB2-HS-0.5 Scientific CMOS Camera System and Service Plan

NIST's Biosystems and Biomaterials Division is procuring a scientific CMOS camera system to advance gene therapy nanoparticle measurement research. - Government Buyer: - National Institute of Standards and Technology (NIST) - Material Measurement Laboratory, Biosystems and Biomaterials Division - OEM Highlight: - Oxford Instruments (Andor) - Vendors Mentioned: - Oxford Instruments Andor - Products Requested: - 1x Andor CB2-HS-0.5 Scientific CMOS Camera System - 0.5 Megapixel sCMOS sensor (816 x 624), 9 µm pixel size, 7.3 x 5.6 mm sensor size - Peak quantum efficiency ≥74%, read noise as low as 2.6 e - Global shutter, 1594 fps full-frame at 8-bit, CoaXPress interface - Multiple ROI support, 8/10/12/14-bit digitization, active cooling compatible, standard C-mount - 1x Operations and Maintenance Manual (electronic or hardcopy) - 1x Customer Assurance Service Plan (12 months) - Priority support, live assist, repairs (parts/labor), 20 business day turnaround, shipping covered, priority helpdesk, categorized response times, troubleshooting, software patching - Unique/Notable Requirements: - Equipment must be new and meet all technical specifications - Rapid, multi-attribute measurement capability for gene therapy nanoparticle characterization - Delivery required within 120 days after award; inspection/acceptance within 30 days - Service plan starts upon Government acceptance, covers 12 months - Technical capability and lowest price are emphasized for award - NAICS code: 334516 (Analytical Laboratory Instrument Manufacturing)

Description

The gene therapy manufacturing innovations in measurement sciences (IMS) project, in the Biosystems and Biomaterials Division, Material Measurement Laboratory, National Institute of Standards and Technology, aims to develop light scattering microscopy methods to characterize gene delivery particles. Emerging gene therapy treatments use gene delivery nanoparticles, such as viral vectors and non-viral carriers, to cure intractable diseases. These manufactured particles suffer heterogeneity issues that hinder treatment efficacy and safety. This project aims to develop light-scattering microscopy methods to enable rapid, multi-attribute measurements of individual gene therapy nanoparticles’ physical characteristics, speeding the development of new treatments and improving their efficacy and safety.

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