SAM #75N98026Q00988

NIH Solicitation for Pharmacokinetic Study of Small-Molecule Compound NCGC00592266

The National Institutes of Health (NIH), Office of the Director, Office of Logistics and Acquisition Operations, is seeking a contractor to conduct pharmacokinetic (PK) studies for a small-molecule compound. - Government Buyer: - National Institutes of Health (NIH), Office of the Director, Office of Logistics and Acquisition Operations - Products/Services Requested: - Pharmacokinetic (PK) study of small-molecule compound NCGC00592266 in mice - Intraperitoneal administration at 10 mg/kg daily for 7 days - Sample collection from plasma, brain, liver, and pancreas at multiple time points - Analytical results and PK data to be provided in Excel format - Blood work and PK results required on days 1 and 14 - Results to be reported to NCATS via email and biweekly conference calls - Unique/Notable Requirements: - Focus on understanding PIP4Kgamma biology and therapeutic potential - Strict deliverable schedule with documentation and presentation of results within one month after purchase order receipt - Biweekly conference calls for progress updates - No specific OEMs or commercial vendors are named in the solicitation - The requirement is for specialized research and laboratory services, not for commercial off-the-shelf products

Description

(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes only solicitation; proposals are being requested, and a separate written solicitation will not be issued.(ii) The solicitation number is 75N98026Q00988. This solicitation is issued as a competitive combined synopsis/solicitation for commercial products or commercial services. The Government intends to award a contract or purchase order resulting from this solicitation using full and open competition.This acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Products or Commercial Services, and is not expected to exceed the simplified acquisition threshold (if applicable).The National Institutes of Health (NIH), Office of the Director, Office of Acquisitions, seeks to award a (Firm-Fixed-Price) to the offeror responsible whose proposal represents the best value to the Government.(iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular effective August 7, 2026(iv) The associated NAICS code is 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) and the small business size standard is 1000 employees.This requirement is unrestricted.

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