SAM #1333ND26QNB640413

NIST Solicitation for PCO Dimax 3.6 ST Ultra High-Speed Camera System for Gene Therapy Research

This opportunity is issued by the National Institute of Standards and Technology (NIST), specifically the Biosystems and Biomaterials Division within the Material Measurement Laboratory, to procure an ultra high-speed camera system for advanced gene therapy measurement sciences research. - Government Buyer: - National Institute of Standards and Technology (NIST) - Material Measurement Laboratory, Biosystems and Biomaterials Division - OEMs and Vendors: - Brand name requirement: PCO (notably, the PCO Dimax 3.6 ST model) - Products/Services Requested: - Ultra High Speed Camera System (PCO Dimax 3.6 ST or equivalent) - Quantity: 1 - Key technical requirements: - 3.6 Megapixel resolution - Up to 56,338 frames per second (fps) maximum; 2,166 fps at full resolution - 8x10 Gb Camera Link HS interface - Signal precision, low non-linearity, and vibration mitigation - Liquid cooling - Selectable gain modes - Software compatibility with pco.camware and Python SDK - Operations and Maintenance Manual - Quantity: 1 - Provided in electronic or hardcopy format - Unique or Notable Requirements: - Brand name justification for PCO Dimax 3.6 ST camera - 100% Small Business Set-aside - Delivery required within 120 calendar days of award - One-year warranty starting upon government acceptance - Camera will be used for multispectral light scattering microscopy to characterize gene therapy nanoparticles

Description

The gene therapy manufacturing innovations in measurement sciences (IMS) project, in the Biosystems and Biomaterials Division, within the Material Measurement Laboratory of the National Institute of Standards and technology, pursues the goal of developing light scattering microscopy methods to characterize gene delivery particles. Emerging gene therapy treatments use gene delivery nanoparticles, such as viral vectors and non-viral carriers, to cure intractable diseases. These manufactured particles suffer heterogeneity issues that hinder treatment efficacy and safety. This project aims to develop light-scattering microscopy methods to enable rapid, multi-attribute measurements of individual gene therapy nanoparticles’ physical characteristics. Such measurements will speed the development of new gene therapy treatments and improve their efficacy and safety.

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