SAM #75N98026Q00878

NIH Sole-Source Procurement for iPSC Quality Control and Organoid Generation Services

This opportunity involves a specialized procurement by the National Institutes of Health (NIH), Office of the Director, Office of Logistics and Multiple Acquisition Operations, for advanced scientific services supporting neurogenomics research on Sex Chromosome Aneuploidies. - Government Buyer: - National Institutes of Health (NIH), Office of the Director, Office of Logistics and Multiple Acquisition Operations - OEM/Vendor: - Oxford StemTech Ltd (sole-source provider) - Services Requested: - Quality control of 94 Induced Pluripotent Stem Cell (iPSC) lines across 9 karyotype groups - Includes cell culture, quality assessment, and provision of two cryovials per line - Generation and characterization of organoids from 26 selected iPSC lines - Organoid differentiation and growth characterization - Assembloid formation and Multi-Electrode Array (MEA) assay - Single-cell RNA sequencing (scRNA-seq) library preparation - Microscopy and neuronal activity assessment - Shipment of prepared libraries to NIH for sequencing - Notable Requirements: - Focus on high-complexity, specialized scientific services for iPSC quality control and organoid generation - Supports research into neurogenomics and Sex Chromosome Aneuploidies - Non-competitive, sole-source justification due to the unique expertise required

Description

This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested, and a separate written solicitation will not be issued.(ii) The solicitation number is 75N98026Q00878/PCA-NIMH-02470. This solicitation is issued as a Notice of Intent (NOI) for a non-competitive combined synopsis/solicitation to award a contract or purchase order without providing for full and open competition (including brand-name, if applicable).This acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Products or Commercial Services, and is not expected to exceed the simplified acquisition threshold. Additional authority includes 41 U.S.C. 1901 and FAR 6.302-3(a)(2)(ii).The National Institutes of Health (NIH), Office of the Director, Office of Acquisitions, intends to negotiate and award a firm fix-price award on a non-competitive basis to Oxford StemTech Ltd The Oxford Science Park Hayakawa Building Edmund Hally Road Oxford, UK to acquire scientific support services for the quality control of Induced Pluripotent Stem Cells (iPSCs) and use of a subset of these iPSC lines for generation and characterization of organoids.

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