NIH Reporter #1R41AG097311-01

Grant for Scalable cGMP Production of SV2A PET Tracers Using Photoredox Chemistry

This opportunity is a grant solicitation from the National Institute on Aging (NIA), part of the National Institutes of Health (NIH), focused on advancing Alzheimer's disease diagnostics. - Government Buyer: - National Institutes of Health (NIH) - National Institute on Aging (NIA) - Purpose: - Develop scalable cGMP (Current Good Manufacturing Practice) production methods for SV2A PET tracers using photoredox chemistry - Enable early detection of Alzheimer's disease through improved 18F-labeled synaptic imaging agents - Products/Services Requested: - Research and development of novel photoredox radiolabeling methods for SV2A PET tracers - Optimization of synthetic methods for clinical trial applications - Unique/Notable Requirements: - Emphasis on scalable, cGMP-compliant production - Application of photoredox chemistry for radiolabeling - No specific OEMs, vendors, part numbers, or purchase quantities identified - Eligibility: - Open to US-based organizations - No detailed product or service line items provided in the solicitation

Description

This NIH grant opportunity aims to develop scalable synthetic methods for producing 18F-labeled synaptic imaging agents to enable early detection of Alzheimer's disease. The project involves developing and optimizing a novel photoredox radiolabeling method. The award is managed by the National Institute on Aging and conducted by SYNVEST IMAGING INC. located in Chapel Hill, NC. The project duration is approximately two years, starting in September 2025.

View original listing