NIH Reporter #5R03AI182671-02

Grant for Research on Cord Blood Vδ2 T Cell Differentiation Using Single-Cell Sequencing

This opportunity is a research grant from the National Institute of Allergy and Infectious Diseases (NIAID) in partnership with the University of Maryland Baltimore, focused on neonatal immune system analysis. - Government Buyer: - National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH) - Collaboration with University of Maryland Baltimore - Products/Services Requested: - Research services to analyze cord blood Vδ2 T cell differentiation and function - Utilization of advanced single-cell sequencing techniques: - CITE-seq (Cellular Indexing of Transcriptomes and Epitopes by Sequencing) - ASAP-seq (Assay for Transposase-Accessible Chromatin with Select Antigen Profiling by sequencing) - Unique/Notable Requirements: - Focus on neonatal immune responses - Emphasis on advanced single-cell sequencing methodologies - Research aims to inform vaccine development and infectious disease prevention - No specific OEMs or commercial vendors are named in the solicitation - Estimated grant value is $80,300 - No product part numbers or quantities specified

Description

This is a research grant opportunity focused on studying neonatal immune responses, specifically analyzing Vδ2 T cells using advanced single-cell sequencing techniques such as CITE-seq and ASAP-seq. The project aims to improve understanding of immune mechanisms in early life to inform vaccine development and infectious disease prevention. The solicitation is issued by the National Institute of Allergy and Infectious Diseases (NIAID) and involves research and development in infectious disease and life sciences. The estimated contract value is $80,300, and the response deadline is May 16, 2025.

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