NIH Reporter #5R00CA267261-04

NCI Grant for Research on Bone Marrow Niche Regulation of Tumor Cell Dormancy and Metastasis

This opportunity is a grant from the National Cancer Institute (NCI) for advanced research on breast cancer dormancy and metastasis, administered through the University of Minnesota. - Government Buyer: - National Cancer Institute (NCI), part of the National Institutes of Health (NIH) - University of Minnesota, Minneapolis, MN (grant recipient) - OEMs and Vendors: - No specific Original Equipment Manufacturers (OEMs) or commercial vendors are named in the notice - Products/Services Requested: - Cancer research services focused on the bone marrow microenvironment's regulation of disseminated tumor cell dormancy, reactivation, and metastasis - Development of mouse models for studying tumor cell behavior - Spatial analysis of patient biopsy samples - Creation of biomaterial models to simulate the bone marrow niche - Unique or Notable Requirements: - Principal Investigator: Grace Gilmore Bushnell - Requires expertise in cancer biology, mouse model development, spatial analysis, and biomaterial engineering - Project is valued at $249,000 - Emphasis on translational research to understand and potentially intervene in breast cancer metastasis

Description

This NIH grant opportunity focuses on research related to breast cancer dormancy and metastasis, specifically investigating the bone marrow microenvironment. The project includes developing mouse models, conducting spatial analysis of patient biopsies, and creating biomaterial models. The research is led by Principal Investigator Grace Gilmore Bushnell at the University of Minnesota. The funding agency is the National Cancer Institute (NCI). The award amount is $249,000 with a project period from February 10, 2022, to August 31, 2027.

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