NIH Reporter #1R21ES036190-01A1

NIEHS Research Grant: NF-κB Regulation by DNA Damage Response Mechanisms

This opportunity is a research grant solicitation from the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health, focused on the regulation of NF-κB by DNA damage response mechanisms. - Government Buyer: - National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health - OEMs and Vendors: - No specific OEMs or vendors are mentioned, as this is a research grant rather than a procurement of goods - Products/Services Requested: - Research grant for investigation into innate immune signaling pathways triggered by DNA damage-induced transcription blockage - Identification of new signaling mechanisms - Assessment of physiological impact of environmental agents affecting transcription and DNA repair pathways - Unique or Notable Requirements: - Open to academic institutions (e.g., Schools of Medicine) - Standard NIH grant application format - No unique license or classification requirements - Estimated grant value: $431,750 - Multiyear award structure

Description

This is a research grant opportunity focused on the regulation of NF-κB by DNA damage response mechanisms, specifically targeting innate immune signaling pathways triggered after DNA damage-induced transcription blockage. The project aims to identify new signaling mechanisms and assess the physiological impact of environmental agents affecting transcription and DNA repair pathways. The grant is issued by the National Institute of Environmental Health Sciences (NIEHS) and is open for applications. The project duration is from January 9, 2025, to January 8, 2027, with an estimated value of $431,750.

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