NIH Reporter #1R56NS143746-01A1

NIH NINDS Awards UCSF for Advanced Epilepsy Imaging Research in Zebrafish

This opportunity involves a research award from the National Institute of Neurological Disorders and Stroke (NINDS), part of the NIH, to the University of California, San Francisco (UCSF) for advanced epilepsy research in zebrafish. - Government Buyer: - National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH) - Recipient Institution: - University of California, San Francisco (UCSF) - Project Overview: - Large-scale imaging of epileptic networks in zebrafish - Utilizes advanced techniques: calcium imaging, hybridization chain reaction, and electrophysiology - Focus on studying seizure dynamics and interneuron regulation in epilepsy - Products/Services Requested: - Research project (single line item) - No specific equipment, OEMs, or vendors identified in the notice - Notable Requirements: - Emphasis on innovative imaging and genetic analysis methods - Supports PA-25-301 funding opportunity - Classified under nursing research and schools of medicine - Estimated Value: - $82,000 for the research project

Description

This project involves the use of advanced brain imaging and genetic zebrafish models to study epileptic networks. Techniques such as calcium imaging, hybridization chain reaction, and electrophysiology will be employed. The goal is to understand seizure dynamics and interneuron regulation in epilepsy. The project is funded by the NIH, specifically the NINDS, and is led by Professor Scott C. Baraban at the University of California, San Francisco.

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