NIH Reporter #1U01AI201044-01

NIH Grant Solicitation: Research on Airway Chemosensory Tuft Cells and Inflammation Mechanisms

This opportunity is a research grant solicitation from Brigham and Women's Hospital in Boston, acting as the government buyer under the NIH.
- Seeks research proposals focused on airway chemosensory tuft cells
- Emphasis on ligand-receptor interactions related to allergen and danger sensing
- Investigate the role of tuft cells in inflammation and airway diseases
- Define mechanisms of tuft cell signal propagation and engagement with nociceptors affecting lung inflammation
- No specific OEMs, vendors, part numbers, or product quantities are listed
- Open to independent hospitals and research organizations
- Unique requirements: advanced biomedical research in immunology, airway disease, and cellular signaling mechanisms

Description

This NIH grant opportunity supports research on airway chemosensory tuft cells, focusing on ligand-receptor interactions relevant to allergen and danger sensing, and their role in inflammation and airway diseases. The project aims to define how tuft cells propagate activation signals and engage nociceptors to influence lung inflammation. The solicitation is open for applications with a response due date of July 3, 2026. The research is to be conducted in Boston, MA, at Brigham and Women's Hospital.

View original listing