NIH Reporter #7R01DA047924-06

NIH Grant for Research on Allosteric Modulators of Dopamine Transporter for NeuroAIDS Therapy

This opportunity is a research grant solicitation from the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH), focused on developing new therapeutic agents for NeuroAIDS. - Government Buyer: - National Institute on Drug Abuse (NIDA), NIH - Scope of Work: - Research and development of allosteric modulators targeting the dopamine transporter - Design, synthesis, and evaluation of novel compounds - Aim to mitigate effects of Tat and cocaine on monoamine transporters - Intended therapeutic benefit for HIV-infected individuals with substance use disorders - Eligible Applicants: - Academic institutions (e.g., University of Alabama at Birmingham mentioned as a prospective bidder) - Products/Services Requested: - Research and development services (no specific part numbers or quantities) - Unique Requirements: - Focus on novel compound development for neuropharmacological applications related to HIV and substance abuse - Emphasis on translational research for new therapeutic strategies - No specific OEMs or commercial vendors are listed in the solicitation.

Description

This is a renewal application for a NIH R01 grant focusing on allosteric modulators of dopamine transporter for NeuroAIDS. The project aims to design, synthesize, and evaluate novel compounds to mitigate Tat and cocaine effects on monoamine transporters. The goal is to develop potential therapeutic agents for HIV-infected individuals with substance use. The solicitation is issued by the National Institute on Drug Abuse (NIDA), part of the NIH.

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