NIH Reporter #1R21AI196701-01A1

NIAID Grant for Research on ITAM-Containing Receptors in Jawless Vertebrates

This opportunity is a research grant solicitation from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, focused on immunological research in jawless vertebrates. - Government Buyer: - National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health - OEMs and Vendors: - No specific OEMs or commercial vendors are named; the opportunity is open to qualified research institutions - Products/Services Requested: - Research on ITAM-containing receptors in jawless vertebrates - Includes analysis of novel ITAMs to optimize engineered antigen receptor design - Involves in vitro testing in human T cells - Protein identification in lamprey leukocytes - Associated with FOA PA-25-304 - Unique or Notable Requirements: - Focus on uncharacterized ITAM-containing receptors and their signal transduction mechanisms - Research to be conducted at Emory University, Atlanta, GA - Open to research institutions with relevant expertise - Estimated grant value is $233,444 - Multi-year period of performance (FY 2026-2028)

Description

This NIH grant opportunity focuses on researching signal transduction mechanisms of uncharacterized ITAM-containing receptors in jawless vertebrates. The project aims to analyze novel ITAMs to optimize engineered antigen receptor design, involving in vitro testing in human T cells and protein identification in lamprey leukocytes. The research is funded for fiscal years 2026-2028 with a total award amount of $233,444. The project is led by Byron Benton Au-Yeung at Emory University under the National Institute of Allergy and Infectious Diseases (NIAID).

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