NIH Reporter #1ZIAEB000094-06

Mechanobiology Research Project Solicitation – Advanced AFM Techniques for Cancer and Immune Cell Studies

The National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the National Institutes of Health, is seeking proposals for a Mechanobiology research project. - Government Buyer: - National Institutes of Health (NIH) - National Institute of Biomedical Imaging and Bioengineering (NIBIB) - Project Scope: - Development of advanced atomic force microscopy (AFM) techniques - Focus on studying mechanical properties of cells and tissues - Special emphasis on pancreatic cancer and T lymphocyte mechanobiology - Products/Services Requested: - No specific products, part numbers, or quantities identified - No OEMs or vendors specified - Notable Requirements: - Research must address mechanobiology in cancer and immune cells - Emphasis on innovative AFM methodologies - No line items or detailed equipment/service requirements provided

Description

This project focuses on developing advanced atomic force microscopy (AFM) techniques to assess the mechanical properties of cells and tissues, with specific emphasis on pancreatic cancer and T lymphocyte mechanobiology. The research aims to understand the role of cellular structures such as the glycocalyx, actomyosin cytoskeleton, and immune synapse in cancer progression and immune response. The solicitation is issued by the National Institute of Biomedical Imaging and Bioengineering (NIBIB). No specific line items or bid response format are provided.

View original listing