Opportunity

NIH Reporter #1ZIAAI001342-05

NIAID Solicitation for Research on Memory B Cell Responses to Pathogenic Viruses

Buyer

National Institute of Allergy and Infectious Diseases (NIAID), NIH, US

Posted

July 20, 2026

Identifier

1ZIAAI001342-05

NAICS

541714, 541715

The National Institute of Allergy and Infectious Diseases (NIAID) is seeking research services to advance understanding of memory B cell responses to major pathogenic viruses. - Government Buyer: - National Institute of Allergy and Infectious Diseases (NIAID), United States - Scope of Work: - Research on the origin, maturation, and plasticity of protective memory B cell responses - Focus on viruses: Dengue, Zika, hepatitis C, HIV-1, and influenza - Development of biologics and small molecules targeting human pathogens - Investigation of antigenic sin, antibody-dependent enhancement, and IgM-derived biologics - Products/Services Requested: - Scientific and technical consulting - Life sciences research and development - OEMs and Vendors: - No specific OEMs or vendors are named in the solicitation - Unique/Notable Requirements: - Emphasis on translational research to develop new therapeutics - Study of immune response mechanisms relevant to vaccine and biologic development - Estimated Contract Value: - $1,162,204

Description

This project involves studying the ontogeny, maturation, and plasticity of protective memory B cell responses in multiple virus models including Dengue, Zika, hepatitis C, HIV-1, and influenza. The aim is to develop biologics and small molecules against relevant human pathogens. The project also investigates antigenic sin, antibody-dependent enhancement, and the development of IgM-derived biologics. The research falls under scientific and technical consulting and life sciences R&D.

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