NIH Reporter #1R03CA303759-01

NCI Solicitation for Caspase-2 Deficient AML Mouse Model Research

This opportunity from the National Cancer Institute (NCI) seeks research services to study caspase-2 in acute myeloid leukemia (AML) using specialized mouse models. - Government Buyer: - National Cancer Institute (NCI), part of the National Institutes of Health (NIH) - Collaboration with Baylor College of Medicine, Department of Pediatrics, Houston, TX - Vendors and OEMs: - No specific OEMs mentioned - Primary vendor referenced: Baylor College of Medicine - Products/Services Requested: - Research services focused on mouse models deficient in caspase-2 and mutated nucleophosmin - 1 unit of research service (no part number specified) - Unique/Notable Requirements: - Multiyear grant structure - Focused on biomedical research for AML using genetically modified mouse models - No administrative or procedural requirements highlighted - Estimated contract value: $160,500 - NAICS code listed as 237110, though the project is biomedical research - No specific product line items; only research services requested

Description

This solicitation is for research on caspase-2 in acute myeloid leukemia (AML) using mouse models deficient in caspase-2 and mutated nucleophosmin. The project is a multiyear award with an estimated funding amount of $160,500. The research is conducted under the National Cancer Institute (NCI) at Baylor College of Medicine, Department of Pediatrics in Houston, TX. The project start date is July 10, 2025, and the end date is June 30, 2027.

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