NIH Reporter #1S10OD040142-01

Procurement of Orbitrap Astral Mass Spectrometer with UHPLC for Proteomics Research

Case Western Reserve University, supported by NIH grant PAR-24-264, is seeking proposals for advanced proteomics instrumentation. - Government Buyer: - Case Western Reserve University, School of Medicine (Cleveland, Ohio) - Funded by the National Institutes of Health (NIH) - OEMs and Vendors: - Thermo Fisher Scientific (manufacturer of Orbitrap instruments) - Products/Services Requested: - Orbitrap Astral Mass Spectrometer with ultra-high pressure liquid chromatography (UHPLC) - No specific part numbers or purchase quantities provided - Notable Requirements: - Instrumentation will support structural and quantitative proteomics, biomarker discovery, and disease mechanism research - Estimated contract value is $1,557,366 - Opportunity is open for competitive bids - OEM Highlight: - Thermo Fisher Scientific is the primary OEM, as the Orbitrap Astral is a proprietary instrument

Description

The project involves acquiring and operating an Orbitrap Astral mass spectrometer with ultra-high pressure liquid chromatography for structural and quantitative proteomics. It is funded by NIH grant PAR-24-264 and aims to support research in proteomics, biomarker discovery, and understanding disease mechanisms. The project duration is from June 15, 2026, to June 14, 2027, with a total award amount of approximately $1.56 million. The organization involved is part of Case Western Reserve University located in Cleveland, OH.

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