NIH Reporter #5P30AG066462-07

NIH Grant Award for Alzheimer’s Biomarker Core Research at Columbia University

This opportunity involves a grant award from the National Institute on Aging (NIA), part of the National Institutes of Health (NIH), to Columbia University Health Sciences for the Biomarker Core project focused on Alzheimer’s disease research. - Government Buyer: - National Institutes of Health (NIH) - National Institute on Aging (NIA) - Awardee: - Columbia University Health Sciences - OEMs and Vendors: - No specific OEMs or commercial vendors are mentioned in the notice - Products/Services Requested: - Biomarker research and development services - Analysis of cerebrospinal fluid (CSF), positron emission tomography (PET), magnetic resonance imaging (MRI), and blood - Measurement of amyloid, tau, and neurodegeneration - Banking and distribution of fluid and neuroimaging biomarker data - Quantification and development of new biomarkers (immune response, endosomal trafficking, vascular pathways) - Expansion of plasma-based markers - Optimization of biomarker deployment - Integration of PET neuroimaging - Implementation of biomarker research among diverse populations - Unique/Notable Requirements: - Emphasis on collaborative research infrastructure - Focus on expanding and optimizing biomarker use in Alzheimer’s disease research - No specific products, part numbers, or purchase quantities listed - No mention of commercial equipment or software procurement

Description

This NIH grant opportunity focuses on the Biomarker Core at Columbia University Health Sciences, aiming to analyze cerebrospinal fluid, PET, MRI, and blood to measure amyloid, tau, and neurodegeneration related to Alzheimer's disease. The project involves banking and distributing biomarker data, quantifying biomarkers, and developing new biomarkers for immune response and vascular pathways. It seeks to expand plasma-based markers, optimize biomarker deployment, integrate PET neuroimaging, and lead biomarker implementation among diverse populations to enhance understanding of Alzheimer's disease pathogenesis and treatment.

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