NIH Reporter #1K08HL185919-01

Research Grant for Immunometabolic Mechanisms in Chronic Lung Transplant Rejection

This opportunity is a federally funded research grant from the National Heart Lung and Blood Institute (NHLBI), part of the National Institutes of Health, focused on chronic rejection after lung transplantation. - Government Buyer: - National Heart Lung and Blood Institute (NHLBI), National Institutes of Health - Administered through Washington University in Saint Louis, Missouri - Products/Services Requested: - Research services to investigate immunometabolic mechanisms driving chronic rejection in lung transplant patients - Establishment of a mouse model for chronic rejection - Metabolic profiling of animal models - Development of targeted drug therapies - Unique or Notable Requirements: - Use of animal models (mice) for research - Advanced metabolic profiling techniques - Focus on translational research to develop new therapies - No specific OEMs or commercial vendors are named in the notice - Estimated contract value is $169,140 for the fiscal year - Open to standard research proposal submissions

Description

This NIH grant opportunity focuses on research into immunometabolic mechanisms that drive chronic rejection following lung transplantation. The project includes establishing a mouse model, conducting metabolic profiling, and developing targeted drugs. Funded by the National Heart Lung and Blood Institute (NHLBI), the award amount is $169,140 for fiscal year 2026. The project duration is from July 1, 2026, to April 30, 2031, and the primary investigator is Marlene Cano at Washington University in Saint Louis.

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