NIH Reporter #1UG3AG097136-01

Development of Bone-Targeted Nanoparticles for Fracture Healing in Aging Populations

This opportunity from the National Institute on Aging (NIA) supports the development of bone-targeted nanoparticles to enhance fracture healing in older adults. - Government Buyer: - National Institute on Aging (NIA), part of the U.S. Department of Health and Human Services - OEMs and Vendors: - No specific OEMs or vendors are named in the notice - Products/Services Requested: - Nanoparticle Development - Creation of bone-targeted nanoparticles for therapeutic use - Preclinical Testing - Safety and efficacy studies of the developed nanoparticles - Clinical Translation - Activities to advance the nanoparticles toward human clinical use - Notable Requirements: - Focus on research and development in physical, engineering, and life sciences - Emphasis on safety, efficacy, mechanism, and IND-enabling studies - Work to be performed in Eugene, Oregon - Total estimated and awarded value: $886,403 - Classified under NAICS codes 237110 and 541712

Description

This project involves the development of nanoparticle-based therapeutics targeting macrophages to improve fracture healing in aging populations. The program includes phases for safety, efficacy, mechanism studies, and IND-enabling studies. The scope covers nanoparticle development, preclinical testing, and clinical translation. Funding is provided by the National Institute on Aging (NIA).

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