Opportunity
NIH Reporter #1R01AR085556-01A1
NIAMS, NIH Research Grant: PBAF Complex and Epidermal Differentiation Gene Regulation
Posted
July 12, 2026
Identifier
1R01AR085556-01A1
NAICS
541714
This opportunity is a research grant solicitation from the National Institute of Arthritis, and Musculoskeletal, and Skin Diseases (NIAMS), part of the NIH, focused on understanding gene regulation in skin cells. - Government Buyer: - National Institute of Arthritis, and Musculoskeletal, and Skin Diseases (NIAMS), NIH - Research Focus: - Investigating the dynamic regulation of epidermal differentiation genes by the cell-state-specific PBAF interactome - Aims to uncover molecular mechanisms relevant to skin disorders such as eczema, psoriasis, and squamous cell carcinoma - Eligible Participants: - Open to research organizations; Northwestern University is listed as a prospective bidder - Products/Services Requested: - Submission of a full research proposal aligned with the scientific objectives - No specific OEMs, commercial products, or part numbers are referenced, as this is a research grant - Notable Requirements: - Research must address the role of the PBAF complex in epidermal differentiation - Alignment with funding announcement objectives is required - Estimated Funding: - Approximately $524,335 for the project - Period of Performance: - Multiyear grant, spanning several years - Classification Codes: - 93.846 (Dermatology, Skin, and Related Research) - NAICS 237110 is referenced but appears unrelated to the research focus
Description
This is a research grant opportunity from the National Institute of Arthritis, and Musculoskeletal, and Skin Diseases (NIAMS), NIH. The project focuses on the regulation of epidermal differentiation genes through the PBAF complex, aiming to uncover molecular mechanisms that could inform therapeutic strategies for skin disorders such as eczema, psoriasis, and squamous cell carcinoma. The award is multiyear, starting in June 2026 and ending in April 2031, with a total funding amount of approximately $524,335. The principal investigator is Xiaomin Bao at Northwestern University.