NIH Reporter #1R21AI188026-01

Development of Intein-Based QF2 System for Mosquito Neurobiology Research

This opportunity is issued by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, for advanced research in mosquito neurobiology: - Government Buyer: - National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health - Project location: Texas A&M University Health Science Center, College Station, Texas - Products/Services Requested: - Development of an intein-based QF2 system for controllable protein expression in the nervous system of Aedes aegypti mosquitoes - Single lump sum bid requested for the complete development effort - OEMs and Vendors: - No specific OEMs or commercial vendors are named in the solicitation - Unique/Notable Requirements: - Focus on synthetic biology and neurobiology research for vector control - Intended to advance genetic tools for mosquito population control - No unique licensing, classification, or set-aside requirements specified - No restrictions on eligible offerors - Quantities and Part Numbers: - One (1) intein-based QF2 system to be developed (no part number specified)

Description

This NIH grant opportunity seeks to develop an intein-based QF2 system for controllable protein expression specifically in the nervous system of the mosquito Aedes aegypti. The project focuses on synthetic biology, neurobiology, and vector control strategies to aid in controlling mosquito populations. The work is conducted under the National Institute of Allergy and Infectious Diseases (NIAID) at Texas A&M University Health Science Center. The estimated contract value is $423,125, and the solicitation is currently open with a response deadline of May 27, 2024.

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