SAM #HT942626QE044

US Army Solicits Genotyping Analysis Services Using Illumina Global Diversity Array

This opportunity is for large-scale genotyping analysis services to support military health research at the U.S. Army Research Institute of Environmental Medicine (USARIEM), under the Defense Health Agency. - Government Buyer: - Department of War, U.S. Army Research Institute of Environmental Medicine (USARIEM), Military Nutrition Program - Defense Health Agency, Medical R&D Contracting Division 1 - OEM Highlight: - Illumina is the specified and required Original Equipment Manufacturer (OEM) - Vendors: - No specific vendors or resellers are named; the requirement is for a contractor with experience in large-scale genomics analysis - Products/Services Requested: - Genotyping analysis services for 648 biological (blood) samples - Use of the Illumina Infinium Global Diversity Array (GDA), featuring approximately 1.8 million genome-wide markers - Deliverables include full data releases, reports, and supporting files within 90 days of sample receipt - Statistical analysis, data interpretation, and consultation on data analysis - Unique/Notable Requirements: - Contractor must have prior experience analyzing at least 10,000 samples for the Federal government - All analyses must use the Illumina Infinium Global Diversity Array platform - Services must include quality controls, repeat analyses as needed, and comprehensive reporting - Performance period is 12 months from award, with all services and deliverables due within this timeframe

Description

The US Army Army Research Institute of Environmental Medicine (USARIEM) requires requires assessing the genome of soldiers who volunteer for research studies. The Military Nutrition Division requires a vendor capable of delivering large-scale, high-density array-based genotyping services for 648 DNA samples collected as part of the Military Health and Nutrition Examination Survey (MHANES). Genomics analysis (i.e., targeted measurement of millions of Single Nucleotide Polymorphisms [SNPs] in the genome and assessment of specific SNPs) is required to support analyses in ongoing research studies. Genomic analysis of DNA using array-based genotyping enables targeted and reproducible measurement of hundreds of thousands to millions of known human variants and facilitates high-resolution imputation to tens of millions of additional variants. For this project, the Illumina Global Diversity Array (GDA), which includes approximately 1.8 million genome-wide markers, is required to support population genetic analyses, ancestry inference, polygenic score calculation, and genome-wide association studies (GWAS).

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