SAM #75N98026R00121

NIH NIDDK Seeks Bruker-Compatible NMR and EPR Equipment Upgrades

The National Institutes of Health (NIH), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Laboratory of Chemical Physics (LCP) is seeking advanced NMR and EPR equipment upgrades to support biomolecular research. - Government Buyer: - National Institutes of Health (NIH) - National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) - Laboratory of Chemical Physics (LCP) - OEMs Mentioned: - Bruker Biospin (primary OEM for NMR and EPR equipment) - Products/Services Requested: - Two cryoplatform replacement units equivalent to or newer than Bruker Biospin CCU05, fully compatible with Bruker Neo 600-MHz spectrometers and cryoprobes - One 100-W solid-state amplifier and Q-band loop resonator to replace a failing amplifier on a Bruker Excelsys E580 34 GHz EPR spectrometer - One 600-MHz small-volume (3 mm) cryoprobe with multi-nuclei (1H/13C/15N/19F/31P) capability, compatible with Bruker Neo 600-MHz spectrometers, meeting strict sensitivity, pulse width, lineshape, gradient, and sample volume requirements - Optional: One Q-band pulsed EPR spectrometer (~34 GHz) with cryogen-free cryomagnet, advanced DEER/DQC measurement capability, rapid freeze-quench compatibility, and compact footprint - Optional: Four additional CCU05 or newer equivalent cryoplatforms for continuous high-duty-cycle operation - Unique/Notable Requirements: - All NMR cryoplatforms and cryoprobes must be fully compatible with existing Bruker Neo 600-MHz systems - EPR amplifier and resonator must support DEER measurements and integrate with Bruker Excelsys E580 - Preference for current-generation, high-sensitivity, multi-nuclei cryoprobes - Optional EPR spectrometer must be cryogen-free and support advanced pulsed EPR techniques - All equipment must support advanced biomolecular research applications

Description

The National Institutes of Health (NIH), Office of the Director (OD) is conducting a market survey to determine the availability and technical capability of qualified small businesses, including 8(a) small businesses, small, disadvantaged businesses, woman-owned small businesses, service-disabled veteran-owned small businesses or HUBZone small businesses capable of providing new Brand name or Equal to: Two NMR cryoplatform replacements 1. Quantity two (2) current-generation cryoplatform units equivalent to or newer than Bruker Biospin CCU05 and 2. Equivalent or improved cooling performance relative to the current end-of-life Bruker Biospin CCU04 systems. Interested firms with the capability of providing all the required items shall submit a capability statement to assist the Government in determining in accordance with the Federal Acquisition Regulation 19.104-1. The intended procurement will be classified under North American Industrial Classification (NAICS) code 334516 with a size standard of 1000e. All respondents are required to identify their firm’s size and type of business. Interested firms responding to this market survey must provide (a) capability statement demonstrating their experience, skills and capability to fulfill the Government’s requirements in this notice. The capability statement shall be in sufficient enough details so that the Government can determine the experience and capability of your firm to provide the items and services in this posting/notice. Offers must also be accompanied by descriptive literature, delivery timeframe, warranties and other information that demonstrates that the offer meets all the foregoing requirements. Capability statements must include the name and telephone number, and email address of a point of contact having authority and knowledge to discuss responses with Government representatives. Capability statements in response to the market survey that do not provide sufficient information for evaluation will be considered non-responsive. A copy of the capability statement must be received via email to robinsti@mail.nih.gov Attn: Tina Robinson prior to 4:30 pm eastern standard time on July 16, 2026. Capability statement must reference solicitation# 75N98026R00121. Submission by email must also reference solicitation # 75N98026R00121 on the subject line of the email. Any questions must be sent via email to robinsti@mail.nih.gov and must include solicitation# 75N98026R00121 on the subject line of email. Capability statements, etc will not be returned to firm/sender. This synopsis is for information and planning purposes and is not to be construed as a commitment by the Government, nor will the Government pay for information solicited.

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