NIH Reporter #1ZIAEY000534-13

Research and Clinical Trial Services for ABCA4-Related Retinopathies

The National Eye Institute (NEI), a division of the U.S. government, is seeking bids for a research initiative focused on ABCA4-related retinopathies. - Government Buyer: - National Eye Institute (NEI) - Scope of Work: - Natural history study of ABCA4-related retinopathies - Clinical trial evaluating metformin for slowing disease progression in ABCA4 retinopathy - Both studies involve collection of biological samples and use of advanced imaging techniques - Products/Services Requested: - No specific products or OEMs are named - Two main service line items: research study and clinical trial - Unique/Notable Requirements: - Focus on rare genetic eye disease (ABCA4-related retinopathies) - Use of metformin as an investigational therapy - No special license or classification requirements specified - No attachments provided - Estimated contract value: $615,612

Description

This project involves a natural history study of ABCA4-related retinopathies and a clinical trial for metformin to slow disease progression. The study includes collection of biological samples and advanced imaging techniques. The NIH is the funding agency, with an award amount of approximately $615,612 for FY2025. The solicitation includes two line items: a natural history study and a metformin clinical trial for ABCA4 retinopathy.

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