NIH Reporter #4R01AI176520-03

NIAID HIV Vaccine Candidate Research Grant Opportunity

This opportunity from the National Institute of Allergy and Infectious Diseases (NIAID), part of NIH, seeks research grant applications for HIV vaccine candidate development. - Government Buyer: - National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH) - Scope of Work: - Focused on designing HIV-1 envelope immunogens using multiple founder envelope antigens - Aim to maximize neutralization breadth for HIV vaccine candidates - Includes optimizing immunogen design and delivery strategies - Evaluation of immune responses in non-human primates - Goal to advance candidates to human clinical trials - Products/Services Requested: - No specific products, part numbers, or purchase quantities listed - Solicitation classified as a research grant - Unique Requirements: - Emphasis on multivalent immunogen design - Requirement for preclinical evaluation in non-human primates - Progression to clinical trial readiness is a key milestone - OEMs and Vendors: - No OEMs or commercial vendors specified in the solicitation

Description

This is a research grant opportunity focused on developing HIV vaccine candidates by designing multivalent envelope immunogens to elicit broad neutralizing antibody responses. The project aims to optimize immunogen design and delivery strategies, and to evaluate immune responses in non-human primates. The ultimate goal is to advance these vaccine candidates to human clinical trials. The solicitation is issued by the National Institute of Allergy and Infectious Diseases (NIAID), part of the NIH.

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