Opportunity
NIH Reporter #3K23NS119794-05S1
Research Award for Personalized Seizure Management Post-Cardiac Arrest
Buyer
National Institute of Neurological Disorders and Stroke (NINDS)
Posted
November 27, 2023
Respond By
August 18, 2025
Identifier
3K23NS119794-05S1
NAICS
541715
This opportunity involves a research award from the National Institute of Neurological Disorders and Stroke (NINDS) to the University of California, San Francisco for advancing seizure management after cardiac arrest. - Government Buyer: - National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH) - Awardee: - University of California, San Francisco (UCSF) - Products/Services Requested: - Research and development services focused on personalized seizure treatment post-cardiac arrest - Utilization of EEG and MRI biomarkers to guide treatment protocols - Application of deep learning to physiology time-series data - Causal inference for observational data - Quantitative brain imaging - OEMs and Vendors: - No specific OEMs or commercial vendors are mentioned - Unique/Notable Requirements: - Emphasis on innovative biomedical technology for brain monitoring - Goal-directed seizure treatment protocols based on neuro-recovery biomarkers - Project classified under CFDA Code 93.853 for Schools of Medicine - Estimated Contract Value: - $54,000 - No specific products, part numbers, or quantities listed
Description
This project aims to reduce secondary brain injury and neurological disability from seizures after cardiac arrest by personalizing seizure treatment using EEG and brain MRI biomarkers of neuro-recovery. The study will provide critical knowledge about epileptogenesis after hypoxic-ischemic brain injury and guide the development of goal-directed seizure treatment and patient selection in future clinical trials. The project is led by Dr. Edilberto Amorim, a neurologist with subspecialty training in critical care and epilepsy, and involves the use of biomedical technology innovations in brain monitoring. The project is funded by the National Institute of Neurological Disorders and Stroke (NINDS) and is based at the University of California, San Francisco.