Opportunity

Simpler Grants.gov #RFA-RM-27-013

NIH Solicits AI-Based Clinical Decision Support Tools for Precision Medicine (PRIMED-AI Program)

Buyer

National Institutes of Health

Posted

June 30, 2026

Respond By

October 19, 2026

Identifier

RFA-RM-27-013

NAICS

541512

The National Institutes of Health (NIH) is seeking proposals for the Model-to-Clinic (M2C) for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) Program. - Government Buyer: - National Institutes of Health (NIH) - Scope of Work: - Development and translation of AI-based clinical decision support (CDS) tools - Tools must integrate clinical imaging with other multimodal health data - Solutions should be developed as Software as a Medical Device (SaMD) - Focus on moving from prototype training/testing to clinical application - Aim to enable personalized medicine strategies for significant health challenges - Eligibility: - Open to nonprofits, educational institutions, government entities, businesses, and foreign organizations - OEMs and Vendors: - No specific OEMs or vendors are named in the notice - Products/Services Requested: - Innovative, reliable, cost-effective, and sustainable multimodal AI-based CDS tools - No specific part numbers or quantities provided - Unique/Notable Requirements: - Emphasis on clinical workflow integration and real-world adoption - Solutions must address translation from research to clinical use

Description

This notice of funding opportunity (NOFO) aims to establish the PRIMED-AI Program to support the development of innovative, reliable, cost-effective, and sustainable multimodal AI-based clinical decision support (CDS) tools. These tools integrate clinical imaging with other multimodal health data to improve patient care across various health conditions. The program seeks to promote the adoption of AI-based CDS tools into clinical workflows to enable personalized medicine strategies addressing significant health challenges. The NOFO focuses on translating AI-enabled, image-centered multimodal CDS tools from prototype testing to clinical applications with potential positive impacts on patient outcomes and healthcare processes.

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