Opportunity

Simpler Grants.gov #RFA-RM-27-014

NIH Solicits Validation Center for AI-Enabled Multimodal Clinical Decision Support Tools (PRIMED-AI)

Buyer

National Institutes of Health

Posted

June 30, 2026

Respond By

October 02, 2026

Identifier

RFA-RM-27-014

NAICS

541715

The National Institutes of Health (NIH) is seeking to establish a Validation Center under the PRIMED-AI Program to support the development and evaluation of AI-enabled, multimodal clinical decision support (CDS) tools. - Government Buyer: - National Institutes of Health (NIH) - OEMs and Vendors: - No specific OEMs or vendors are named in the solicitation - Products/Services Requested: - Establishment and operation of a Validation Center dedicated to: - Comprehensive evaluation and characterization of AI-enabled, image-based, multimodal CDS tools - Verification, validation, interoperability, and uncertainty quantification of tools developed by the PRIMED-AI Consortium - Systematic validation of deliverables from related PRIMED-AI initiatives (Playbook, Data-to-Model Academic-Industrial Partnerships, Model-to-Clinic NOFOs) - Unique or Notable Requirements: - The Center must ensure reliability, reproducibility, and generalizability of AI-based CDS tools - Open to a wide range of eligible applicants (government, business, education, nonprofit), but excludes foreign organizations and foreign components - No specific products, part numbers, or OEMs are listed; focus is on service and capability establishment

Description

This funding opportunity aims to establish the PRIMED-AI Program to develop innovative, reliable, cost-effective, and sustainable multimodal AI-based clinical decision support tools integrating clinical imaging with other health data. The program seeks to promote adoption of AI-based tools in clinical workflows for personalized medicine addressing significant health challenges. The NOFO solicits applications to create a Validation Center that will comprehensively evaluate and characterize AI-enabled, image-based multimodal CDS tools developed by the PRIMED-AI Consortium, focusing on verification, validation, interoperability, and uncertainty quantification. The Validation Center will systematically validate deliverables from various award recipients under the PRIMED-AI program.

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