Opportunity
Simpler Grants.gov #RFA-RM-27-001
NIH Director’s Pioneer Award Grant for Innovative Research Projects
Buyer
National Institutes of Health
Posted
June 29, 2026
Respond By
September 09, 2026
Identifier
RFA-RM-27-001
NAICS
541715
The National Institutes of Health (NIH) is inviting applications for the NIH Director’s Pioneer Award, part of the High-Risk, High-Reward Research (HRHR) program under the NIH Common Fund. - Government Buyer: - National Institutes of Health (NIH) - NIH Common Fund, Office of the Director - Purpose: - Supports individual scientists proposing bold, innovative research with potential for major impact in areas relevant to the NIH mission - Open to all research topics (basic, translational, or clinical) as long as the project represents a substantially different scientific direction from current efforts - Funding Details: - Total program funding: $8,000,000 - Expected number of awards: 8 - Each award: $700,000 - Eligibility: - U.S.-based nonprofit, governmental, business, and educational organizations - Foreign organizations are not eligible, but foreign components (as defined by NIH policy) are allowed - No specific OEMs, vendors, or product/service procurements are involved, as this is a grant for research proposals, not a purchase of goods or services - Unique Requirements: - Emphasis on exceptional creativity and high-risk, high-reward research - Projects must be substantially different from current research efforts
Description
The NIH Director's Pioneer Award supports individual scientists of exceptional creativity who propose bold and highly innovative research projects with the potential to produce a major impact on broad, important areas relevant to the mission of NIH. The research must reflect substantially different scientific directions from those already being pursued. Applications in all topics relevant to the broad mission of NIH are welcome, including basic, translational, or clinical research. This award is part of the High-Risk, High-Reward Research program of the NIH Common Fund.