MTEC #MTEC-26-03-PROMPT

Automated, Man-Portable Platform for Field Manufacturing of Nucleic Acid Primers and Probes

This opportunity seeks innovative solutions for field-ready molecular biology manufacturing: - Government Buyer: - Medical Technology Enterprise Consortium, Inc. (MTEC) supporting the Defense Threat Reduction Agency (DTRA) - Products/Services Requested: - Development of a fully automated, man-portable, ruggedized prototype platform for on-demand manufacturing of clinical-quality nucleic acid primers and probes - System must integrate synthesis, purification, and quality control in a compact, battery-operable instrument - Reagents must be stable at room temperature for at least 12 months and function across a wide temperature range - Platform must be operable by non-specialist personnel in austere or far forward environments - Must meet MIL-STD-810 ruggedization standards and minimize hazardous chemistry and cold-chain requirements - Prototypes will be evaluated by government-identified laboratories - OEMs and Vendors: - No specific OEMs or vendors are named; solicitation is open to qualified offerors - Unique/Notable Requirements: - Field-stable, non-hazardous synthesis chemistry - Integrated purification and gold-standard quality control - Regulatory pathway navigation for clinical-quality output - Rapid, on-demand production capability in expeditionary settings - Multiple awards possible

Description

This solicitation is a Request for Project Proposals (RPP) issued by the Medical Technology Enterprise Consortium (MTEC) in support of the Defense Threat Reduction Agency (DTRA). The project focuses on developing a fully automated, man-portable, and ruggedized prototype platform for on-demand, expeditionary manufacturing of clinical-quality nucleic acid primers and probes. The system must be operable by non-specialist personnel in far forward or austere environments and address key challenges such as replacing hazardous synthesis chemistry with field-stable alternatives, integrating purification and quality control, and navigating regulatory pathways. The period of performance is up to 24 months, and multiple awards may be made to qualified offerors.

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