Simpler Grants.gov #RFA-AI-28-008

Forecasted Funding for Clinical Trials in Organ Transplantation in Children and Adults

This opportunity is a forecasted funding announcement from the National Institutes of Health (NIH), specifically the National Institute of Allergy and Infectious Diseases (NIAID), for clinical trials in organ transplantation in children and adults. - Government Buyer: - National Institutes of Health (NIH) - National Institute of Allergy and Infectious Diseases (NIAID) - Program: Clinical Trials in Organ Transplantation in Children and Adults (CTOT-CA) - Purpose: - Support multicenter clinical trials and mechanistic studies to improve outcomes in organ transplantation - Focus on heart, lung, kidney, liver, and intestinal transplantation - Includes non-hematopoietic cellular transplantation, vascularized composite tissue transplantation, and transplantation of bone marrow, mesenchymal stem cells, or immunologically active cells as adjuncts - Funding Details: - Total estimated funding: $11,280,000 - Anticipated number of awards: 4 - Funding instrument: Cooperative agreement - No specific OEMs, vendors, products, or part numbers are identified, as this is a research grant opportunity - Notable Requirements: - Emphasis on multicenter collaboration and mechanistic studies - Research must address both clinical and immunological aspects of transplantation - Open to studies in both pediatric and adult populations

Description

The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance its mission through the continued support of the Clinical Trials in Organ Transplantation in Children and Adults (CTOT-CA) program. The goal of the CTOT-CA is to improve the outcome of organ transplantation through clinical trials with mechanistic studies. The program supports multicenter clinical trials and associated immune mechanism studies in heart, lung, kidney, liver, and intestinal transplantation, as well as trials of non-hematopoietic cellular transplantation, vascularized composite tissue transplantation, and transplantation of bone marrow or mesenchymal stem cells as adjuncts to organ transplantation. The funding instrument is a cooperative agreement with a total funding of $11,280,000 and expected awards of 4.

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