Simpler Grants.gov #362948

NIH Forecast: Research to Develop Improved Drug Susceptibility Tests for Mycobacteria

This opportunity is a forecasted research grant from the National Institutes of Health (NIH), specifically the National Institute of Allergy and Infectious Diseases (NIAID), to support the development of improved drug susceptibility tests (DSTs) for mycobacterial drugs. - Government Buyer: - National Institutes of Health (NIH) - National Institute of Allergy and Infectious Diseases (NIAID) - Purpose: - Fund research to develop innovative DST assays for mycobacterial drugs, including those for tuberculosis (TB) and non-tuberculous mycobacterial (NTM) infections - Focus on rapid genotypic and improved phenotypic methods that do not require full culture growth - Products/Services Requested: - Research and development services for new DST methods - No specific products, part numbers, or OEMs are listed, as this is a research grant - Notable Requirements: - Emphasis on innovation and speed in DST assay development - Includes drugs currently in use, new drugs, and those in late-stage clinical development - Open to a wide range of applicants: nonprofits, government entities, educational institutions, businesses, and tribal organizations - Estimated Funding: - $3,000,000 total, with approximately three awards anticipated - No unique product requirements or OEMs specified, as the focus is on R&D of new testing methods

Description

The National Institute of Allergy and Infectious Diseases (NIAID) seeks to support research to develop improved drug susceptibility tests (DSTs) for mycobacterial drugs, including those used for tuberculosis (TB) and non-tuberculous mycobacterial (NTM) infections, as well as new and late-stage clinical development drugs. The goal is to create innovative DST assays that are rapid and do not require full culture growth, to better guide treatment and reduce drug-resistant mycobacterial rates. This program addresses the rising rates of TB and NTM lung disease and aims to improve current slow, culture-based testing methods. The funding instrument is a cooperative agreement with an expected total program funding of $3,000,000 and approximately three awards anticipated.

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