Opportunity

Simpler Grants.gov #RFA-HG-27-013

NIH GREGoRi Innovation Projects Funding for Rare Disease Diagnosis Research

Buyer

National Institutes of Health

Posted

June 18, 2026

Respond By

October 30, 2026

Identifier

RFA-HG-27-013

NAICS

541715, 541714

This opportunity from the National Institutes of Health (NIH) seeks proposals for the GREGoRi Innovation Projects to advance rare disease diagnosis. - Government Buyer: - National Institutes of Health (NIH) - GREGoRi Program Team - Assistance Listing 93.172 (Human Genome Research) - OEMs and Vendors: - No specific OEMs or commercial vendors are named; the focus is on research and innovation - Products/Services Requested: - Development and testing of highly innovative experimental or computational approaches - Includes new tools, molecular technologies, and analytical methods - Aimed at identifying causal genes or variants underlying rare genetic disorders - Unique or Notable Requirements: - Open to a wide range of applicants: educational institutions, nonprofits, businesses, government entities, and foreign organizations - Funding instrument is a cooperative agreement - Awards up to $500,000 each, with total program funding of $7,500,000 - Emphasis on transformative, novel approaches rather than established products or services - International collaborations are eligible

Description

The Genomics Research to Elucidate the Genetics of Rare Diseases: innovation (GREGoRi) initiative aims to accelerate a paradigm shift in rare disease diagnosis by developing and testing highly innovative experimental or computational approaches. These approaches should have the potential to transform the current state of the art in identifying causal genes or variants underlying rare genetic disorders. The funding opportunity supports projects that reimagine tools, molecular technologies, and analytical methods for rare disease diagnosis.

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