Opportunity

Simpler Grants.gov #361084

NIH Director’s Transformative Research Award Grant Opportunity for Innovative Biomedical Projects

Buyer

National Institutes of Health

Posted

January 06, 2026

Respond By

September 03, 2026

Identifier

361084

NAICS

541715, 541714, 541713

The National Institutes of Health (NIH) is seeking proposals for the NIH Director’s Transformative Research Award under the High-Risk, High-Reward Research (HRHR) Program. - Government Buyer: - National Institutes of Health (NIH), NIH Common Fund - Purpose: - Support bold, groundbreaking, and exceptionally innovative biomedical research projects - Projects should have the potential to create new scientific paradigms, establish new clinical approaches, or develop transformative technologies - Products/Services Requested: - Grant funding for transformative biomedical research (no specific products, part numbers, or quantities specified) - Unique/Notable Requirements: - No preliminary data required for application - Proposals must demonstrate compelling potential for major impact in areas relevant to NIH - Open to a wide range of applicants, including government, business, educational, nonprofit, tribal, and foreign institutions - OEMs and Vendors: - No specific OEMs or vendors are mentioned - Estimated Funding: - $8,000,000 total, with approximately seven awards expected

Description

The NIH Director’s Transformative Research Award supports individual scientists or groups proposing bold, groundbreaking, and innovative research with the potential to create new scientific paradigms or develop transformative technologies. Applications in any biomedical science area are welcome, with no preliminary data required. Projects must demonstrate a compelling potential to produce a major impact relevant to the NIH. This award is part of the High-Risk, High-Reward Research Program of the NIH Common Fund.

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