Simpler Grants.gov #362353

NIH Grant Forecast: National Biomedical Research Centers for Human-Based Research Models and NAMs

This opportunity is a forecasted grant from the National Institutes of Health (NIH) for National Biomedical Research Centers (NBRCs): - Government Buyer: - National Institutes of Health (NIH), Division of Comparative Medicine, Office of Research Infrastructure Programs - Purpose and Scope: - Support NBRCs in providing scientific expertise, advanced equipment, infrastructure, and well-characterized research models to the national research community - Emphasis on developing innovative human-based models and New Approach Methodologies (NAMs), such as in vitro and in silico models - Clinical trials are permitted only if they are human-based NAMs - Eligibility: - Open to nonprofits, government entities, tribal organizations, businesses, and educational institutions - Unique/Notable Requirements: - Focus on reducing, refining, and replacing the use of live animal models in research - Centers with existing nonhuman primate colonies are encouraged to apply - No specific OEMs, vendors, or product part numbers/quantities are listed - No product procurement; this is a grant for research infrastructure and innovation services

Description

The National Biomedical Research Centers (NBRCs) provide scientific expertise, advanced equipment, infrastructure, and well-characterized research models to researchers nationwide. The NOFO emphasizes developing innovative human-based models and new technologies to reduce reliance on live research models, including plans to reduce, refine, and replace whole-animal use. NBRCs function as centers of innovation in fundamental science and translational hubs for novel interventions, with clinical trials allowed only as human-based New Approach Methodologies (NAMs). This open competition aims to increase innovation opportunities at centers with existing nonhuman primate colonies and leverage capabilities in basic and translational research.

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