Simpler Grants.gov #R01

NIH Funding Opportunity: Research on Gut-Brain Axis in Neurological Diseases

This opportunity is issued by the National Institutes of Health (NIH), specifically the National Institute of Environmental Health Sciences (NIEHS), to fund research on the gut microbiome-brain axis and its impact on neurological diseases caused by environmental exposures. - Government Buyer: - National Institutes of Health (NIH) - National Institute of Environmental Health Sciences (NIEHS) - Products/Services Requested: - Research proposals focused on the gut-brain axis in neurological conditions - Development of gut-focused intervention strategies, including: - Probiotics - Microbial biomarkers - Nutritional supplements - Novel therapeutics - Notable Requirements: - Emphasis on collaborative research combining toxicology, microbiome, and neuroscience - Research should target detection, prevention, and intervention for neurological outcomes (e.g., mental health disorders, Parkinson’s, Alzheimer’s) - Foreign components are allowed per NIH Grants Policy Statement - No specific OEMs or vendors are named, but the scope includes products such as probiotics and nutritional supplements - Estimated funding is $4,000,000 with up to 8 expected awards

Description

The National Institute of Environmental Health Sciences (NIEHS) is soliciting applications for research to enhance understanding of the gut microbiome-brain axis to improve detection, prevention, and intervention strategies for neurological diseases caused by environmental exposures. The program covers a broad range of neurological outcomes including mental health disorders and neurodegenerative diseases like Parkinson's and Alzheimer's. The goal is to develop gut-focused interventions such as probiotics, microbial biomarkers, nutritional supplements, and novel therapeutics to reduce risk, slow progression, or reverse neurological conditions. Collaborative research combining toxicology, microbiome, and neuroscience expertise is encouraged. Applications are not currently being solicited; this notice allows potential applicants time to prepare.

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