SAM #ARPA-H-SN-26-159

ARPA-H Solicits R&D Proposals for Home-Based Sleep Measurement and Treatment Technologies (REST Program)

The Advanced Research Projects Agency for Health (ARPA-H), under the Department of Health and Human Services, is seeking proposals for the Restorative and health-Enhancing Sleep Time (REST) program. - Government Buyer: - Agency: Advanced Research Projects Agency for Health (ARPA-H) - Sub-agency: Proactive Health Office (PHO) - Program Objective: - Develop innovative, home-based, closed-loop technologies to objectively measure and treat poor sleep, particularly insomnia - Focus on physiological signal-based systems for both measurement/diagnosis and real-time, noninvasive treatment - Technical Areas Solicited: - TA1: In-home measurement and diagnosis systems with clinical fidelity, capable of classifying insomnia subtypes and linking sleep profiles to health risks - TA2: Closed-loop, noninvasive treatment systems that personalize interventions during sleep based on real-time physiological data - Products/Services Requested: - No specific OEMs, vendors, products, or part numbers are named - Solicitation is for R&D services to develop new sleep health technologies, not for off-the-shelf products - Unique/Notable Requirements: - Solutions must be validated, consumer-grade, and suitable for home use - Emphasis on objective, personalized, and scalable approaches to improve long-term health outcomes - Program includes milestones such as human subject enrollment, technology demonstrations, and FDA submissions - Period of Performance: - 66 months (5.5 years), divided into three phases: concept proof, proof-of-concept, and clinical translation/commercialization

Description

The Advanced Research Projects Agency for Health (ARPA-H) seeks proposals for the Restorative & health-Enhancing Sleep Time (REST) program, a bold effort to transform how poor sleep is measured and treated by enabling objective, home-based, closed-loop technologies that detect health-relevant sleep microstructures and respond to them in real time. If successful, REST will establish the technical foundation for a new generation of sleep health technologies that are objective, personalized, and capable of improving long-term health outcomes at scale.

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