Opportunity
SAM #75N98026Q00528
NIH Solicitation for In Vivo Pharmacokinetic Study of Antibody Conjugates in Transgenic Mice
Buyer
NIH Office of Logistics and Acquisition Operations
Posted
June 04, 2026
Respond By
June 13, 2026
Identifier
75N98026Q00528
NAICS
541380, 541715, 541714
The National Institutes of Health (NIH), NIDDK Intramural Research Program's Laboratory of Bioorganic Chemistry, is seeking services for an in vivo pharmacokinetic study of antibody-lectin conjugates to support HIV prevention research. - Government Buyer: - National Institutes of Health (NIH) - NIDDK Intramural Research Program - Laboratory of Bioorganic Chemistry's Natural Products Chemistry Section - OEMs and Vendors: - Jackson Laboratory (intended awardee) - Products/Services Requested: - In vivo pharmacokinetic study of optimized antibody-lectin conjugates - Study performed in transgenic FcRn mice expressing human Fc neonatal receptor - Intravenous administration of conjugates - Measurement of serum concentrations by ELISA - Unique or Notable Requirements: - Use of transgenic FcRn mice for human-relevant pharmacokinetic data - Focus on HIV prevention research - Small businesses invited to submit capability statements
Description
Attachment: Notice of Intent